
Fludora® Fusion has been developed by Bayer specifically for vector control applications; it is the first product intended for Indoor Residual Spraying (IRS) campaigns combining two unrelated modes of action, the neonicotinoid insecticide clothianidin and the pyrethroid insecticide deltamethrin.
IVCC has supported Bayer in the evaluation of the Fludora Fusion product with the conduct of two trials as part of the World Health Organization (WHO) Prequalification for Vector Control Evaluation (WHO PQT-VC); this included the sponsorship of a community scale trial in Muheza, Tanzania. The product was listed by WHO-PQT-VC in December 2018.
Fludora® Fusion has been proven to be effective against strains of mosquitoes possessing mechanisms of resistance to pyrethroid, carbamate and organophosphate insecticides.
Benefits and features
- Combines two active ingredients with different modes of action (IRAC Group 3A and 4A)
- Provides long-lasting residual activity on a range of surface types, including against pyrethroid resistant mosquitoes (trials indicate that the combination achieved a greater residual effect than the individual components.
- Available in low-volume, unit-dose, sealed, water-soluble sachets, which is highly convenient for the end-user
- Low volume of use reduces overall transport and warehousing costs – 1 kg of product is typically enough to cover 20 structures
- Manufactured and supplied out of Africa
- Provides fast knockdown of mosquitoes – enhancing householder’s perception of efficacy and thus supporting positive perspective of use. (Reference: PQ Decision document)
- The supporting trial data submitted to WHO-PQ indicate that Fludora Fusion should last at least 6 – 8 months depending on the mosquito strain, the surface type and ambient conditions. (Reference: PQ Decision document)
Industry partner
Publications
- Bayer announces WHO pre-qualification for Fludora® Fusion to combat malaria
- Small-scale field evaluation of the efficacy and residual effect of Fludora® Fusion (mixture of clothianidin and deltamethrin) against susceptible and resistant Anopheles gambiae populations from Benin, West Africa
- Indoor Residual Spraying (IRS) with a mixture of clothianidin (a neonicotinoid insecticide) and deltamethrin provides improved control and long residual activity against pyrethroid resistant Anopheles gambiae sl in Southern Benin
- Fludora® Fusion listing, WHO PQT-VC
- Fludora® Fusion, Discover the first two-way IRS solution
- Video: Fludora® Fusion Field Trials