IVCC this week attended Syngenta’s 2017 Good Growth Plan event in Brussels, Belgium. Dr Nick Hamon, CEO of IVCC was interviewed about their partnership programme and spent time with Syngenta CEO Erik Fyrwald. Earlier in the day, David Maguire, IVCC’s NgenIRS Director presented to over 200 invited guests providing an insight on how Syngenta’s malarial insecticide Actellic©CS300 is being used, with the support of IVCC and its funder UNITAID, to deliver next generation indoor residual spray programmes across sub-Saharan Africa.
Sumitomo Chemical & IVCC Deliver Brand New IRS 27th October 2017Sumitomo Chemical and IVCC are proud to announce that Sumishield® 50WG has been prequalified by the World Health Organization (WHO). With a brand-new mode of action chemistry for indoor residual spraying (IRS), Sumishield® 50WG represents a significant breakthrough, providing a new tool to allow program managers to rotate between chemistries and be better equipped to manage resistance.
IVCC supported Sumitomo Chemical by providing scientific advice, laboratory support as well as leading rigorous field trials to prove Sumishield® 50WG’s efficacy.
Dr. Nick Hamon, Chief Executive Officer at Innovative Vector Control Consortium (IVCC), said: “Mosquito resistance to current insecticides is threatening the huge gains made so far in reducing deaths from malaria, so we desperately need effective chemistry with modes of action new to public health to combat these resistant mosquitoes, and enable rotation with other products. News that Sumishield® 50WG has recently obtained a WHO PQ listing is therefore very welcome and will prove to be a very valuable tool in the vector control toolbox.”
“IVCC and its partners on the Unitaid-funded NgenIRS project are looking forward to adding this new third generation indoor residual spray (3GIRS) to the toolbox of insecticides that can be supported through the established reduced pricing mechanism. This will give African malaria programs a second affordable long-lasting insecticide to be used in rotation for resistance management.”
With a single mode of action chemistry based on the neonicotinoid insecticide, clothianidin, Sumishield 50WG gives malaria prevention programs greater flexibility when rotating with other chemistries. The formulation has proven efficacy under WHO supervised trials and continues to work effectively for up to nine months after spraying, even against highly resistant mosquitoes.
Due to a non-repellent formula, mosquitoes are exposed to SumiShield 50WG for longer, increasing mortality and reducing the chances of resistance developing. The odourless spray also has very low mammalian toxicity, doesn’t cause irritation through skin contact and won’t stain walls, which creates better acceptance by householders.
WHO figures show that nearly half the world’s population is at risk of malaria and despite great gains madea drop in both incidence and mortality rates in recent years, there are over 200 million new cases every year. Increased prevention and control measures have led to significant gains, but these are under threat due to insecticide resistance, which affects 75% of countries with ongoing transmission of the disease. Rotating insecticides is one of the key strategies for avoiding resistance, however nearly 87% of affected countries are failing to do this, largely due to a lack of alternative chemistries to choose from.
For further information on the WHO Prequalification of SumiShield, visit : http://www.who.int/entity/pq-vector-control/prequalified-lists/sumishield50wg/en/index.html
A New Insecticide to be Used to Fight Malaria 14th December 2017Geneva/Liverpool – Unitaid, the Innovative Vector Control Consortium (IVCC) and Japan’s Sumitomo Chemical Company (SCC) are excited to announce the use of a new generation insecticide to be used for indoor residual spraying (IRS) to fight malaria.
IRS is a powerful way to rapidly reduce malaria transmission by spraying insecticides on indoor walls and ceilings where malaria-carrying mosquitoes are likely to rest after biting people. However, many mosquitoes become resistant to the insecticides that they come into contact with most often. New insecticides are therefore needed to minimize the threat of resistance.
SCC’s new malaria vector control product – SumiShield® 50WG- will be used in a Unitaid-funded project that aims to create a more sustainable market for next-generation IRS products at affordable prices. This NgenIRS project is being implemented by IVCC and its partners, including the US President’s Malaria Initiative, Abt Associates, PATH and The Global Fund.
The SumiShield product, which was prequalified by the World Health Organization (WHO) in late October 2017, is one of two new insecticides that will allow malaria programmes to pre-emptively rotate new generation insecticides in countries and fight resistance. The formulation has proven effective in WHO-supervised trials and continues to work for up to nine months after spraying, even against highly resistant mosquitoes.
Countries will have the ability to effectively implement the WHO’s Global Plan for Insecticide Resistance Management (GPIRM) now that there are two new generation IRS products to work with and more are expected to enter the market in the next two years. Rotating insecticides is one of the key strategies to manage resistance.
According to WHO, nearly half the world’s population is at risk of malaria and despite great gains made in recent years, there are still over 200 million new cases every year.
Dr. Nick Hamon, IVCC’s Chief Executive Officer, said: “We know vector control saves lives and resistance to insecticides is threatening the huge gains made so far in reducing deaths from malaria. We desperately need effective chemistry with modes of action new to public health to combat these resistant mosquitoes, and enable rotation with other products.”
Since its inception in 2016, the NgenIRS project has supported spray operations in 12 African countries and the procurement of over 4.5 million bottles of the new generation insecticide, sufficient to protect an estimated 58 million people. In 2018, NgenIRS will begin operations in two more malaria endemic countries.
“Unless newer insecticides are identified and used, we run the risk of considerable reversals in the fight against malaria,” said Lelio Marmora, Unitaid’s Executive Director.” We are proud to support the NgenIRS project to combat insecticide resistance and ultimately save lives.”
For further information on the WHO prequalification of SumiShield, and the NgenIRS project, please visit:
IVCC is pleased to announce that it has secured partnership role on a recently granted contract to Abt Associates to reduce the burden of malaria across Africa.
IVCC is part of a five-year, $472 million contract awarded to Abt Associates, under the Prevention of Mosquito-Borne Diseases through Vector Control IDIQ, by The United States Agency for International Development (USAID) through the U.S. President’s Malaria Initiative (PMI). Through this contract, Abt Associates will support PMI and USAID to plan and implement an integrated vector control approach with the overall goal of reducing the burden of malaria in Africa.
As a partner, IVCC will be responsible for advising on the Indoor Residual Spraying (IRS) and other vector control product development pipeline and the timing and availability of products for trials and pilot launches.
IVCC will also be responsible for building and negotiating Public Private Partnerships with manufacturers of new vector control technologies and will, in partnership with Abt Associates and industrial partners, lead the planning and project management of the late stages of product development launch. Through its relationship with Innovation to Impact (I2I), IVCC will also assist in managing products through the WHO/pre-qualification and policy recommendation review processes.
Nick Hamon, CEO of IVCC said: “Since 2000, Africa has seen major reductions in morbidity and mortality from malaria, primarily due to investments in vector control interventions. IVCC will be able to leverage its expertise in integrating best practices and innovative solutions in the field of product development, product introduction, design of sustainable approaches to vector control and resistance management.”
“Through our partnership with Abt, this project gives IVCC increased connectivity to the market place and an additional route for testing new interventions which will further support our Access programmes.”
Tech Update January 2019 15th January 2019View/download the Tech Updates highlighting vector biology and control news, publications and resources.
Given the breadth of vector control related literature, we are unable to include all relevant work. These updates are intended to focus primarily on Anopheles biology and a subset of control topics with global relevance.
Any views expressed in the updates do not necessarily reflect the views or opinions of IVCC. In many cases, we directly quote sections of published work. Mention of trade names or commercial products is solely for the purpose of providing specific information and does not imply recommendation or endorsement by IVCC or its funders.